LONDON (AP) —The stunning string of upsets at Wimbledon continues into the second week. Defending champion Serena Williams lost in the fourth round, falling 6-2, 1-6, 6-4 to Sabine Lisicki of Germany.

The loss ended Williams' career-best 34-match winning streak and her attempt to capture a sixth title at the All England Club.

Williams was up a break twice in the third set but Lisicki fought back both times and broke again to go ahead. She converted her second match point with a forehand winner.

In other play on a busy day at the All England Club, former champion Petra Kvitova became the first player to reach the quarterfinals, beating Carla Suarez Navarro of Spain 7-6, 6-3.

She was joined minutes later by Kirsten Flipkens of Belgium, who reached her first career Grand Slam quarterfinal by ousting Flavia Pennetta of Italy 7-6, 6-3. Li Na routed Roberta Vinci of Italy 6-2, 6-love to reach the quarterfinals for the third time.

Fourth-seeded David Ferrer overcame another slow start with a 6-7, 7-6, 6-1, 6-1 victory over Ivan Dodig of Croatia.

All fourth round matches in men's and women's play are on the schedule.

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